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A breast cancer patient may be diagnosed with being hormone receptor positive. This receptor protein is known as the ______ protein.


A) HER-2
B) p53
C) BRCA1
D) HER-1
E) TP53

F) All of the above
G) A) and B)

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Cancer begins with a series of events. One of these events is becoming immortal. Explain how these cells become immortal.

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Cancer cells become immortal through a p...

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Chromosomes are copied


A) during mitosis.
B) in the growth phase of interphase (G1) .
C) immediately before cell division (G2) .
D) between the growth phase (G1) and preparation for cell division (G2) .

E) All of the above
F) A) and B)

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Cancer ______ are used to protect against some forms of cancer and can be used to warn the body of existing cancers.

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The stages of breast cancer are determined by an oncologist by addressing four questions. Provide three of the four questions.

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eukaryotes...

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A research oncologist is one who studies the causes and treatments of cancer. What area(s) would a research oncologist study to understand the formation of a new cancer?


A) Genetic factors
B) Environmental factors
C) Prevalence in males versus females
D) All of the answer choices are correct.

E) A) and D)
F) A) and C)

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Cells within the inside of a tumor secrete growth factors, which cause capillaries to grow toward the tumor. This process is called ______, and contributes to the growth and spread of the tumor.


A) metastasis
B) angiogenesis
C) biogenesis
D) abiogenesis

E) None of the above
F) A) and B)

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Which characteristic corresponds with Stage 2 of breast cancer?


A) Cancer begins invading more lymph nodes and tissue
B) Cancer is localized and less than 2 cm
C) Cancer extensively spreads to nearby tissue
D) Cancer spreads to other organs
E) Cancer is found in a few lymph nodes

F) A) and B)
G) A) and E)

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Cells are specialized to form tissues and organs through the control of gene expression. Gene expression is regulated (turning on and off genetic instructions) by


A) nearby cell signals.
B) environmental factors.
C) nearby cell signals and environmental factors.
D) rapid cell divisions.
E) nearby cell signals and rapid cell divisions.

F) A) and B)
G) A) and C)

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Some antimetabolites are called antibiotics. From the list below, select all statements that characterize these compounds. (Check all that apply.)


A) They are designed to kill bacteria.
B) They interfere with specific enzyme functions.
C) They interfere with RNA formation during gene expression.
D) They interfere with DNA replication.
E) They can be used to treat any infection.

F) A) and C)
G) A) and B)

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There are three checkpoints during cell division. Which checks for DNA replication?


A) M
B) G2
C) G1

D) A) and B)
E) All of the above

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In ______ radiation, a radioactive substance is either ingested or injected into the blood. It can then be targeted for therapy.

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Mutations in DNA can result in cancerous cells. These cells are structurally altered but their functions remain normal.

A) True
B) False

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The main difference between Stage 0 and Stage 1 cancer is that in Stage 1, the cancer cells have


A) begun to spread to a few lymph nodes.
B) formed a larger tumor.
C) spread to all lymph nodes.
D) spread extensively throughout body.
E) spread to neighboring organs.

F) C) and D)
G) A) and D)

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The main difference between Stages 2A and 2B breast cancer, is that in Stage 2B the tumors in nearby lymph nodes are __________.


A) less than 2 cm
B) between 2-5 cm
C) between 5-10 cm
D) greater than 10 cm

E) All of the above
F) None of the above

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Cancer cells __________.


A) are less specialized
B) no longer function with neighboring cells
C) divide rapidly
D) ignore the genetic information
E) All of the answer choices are correct.

F) D) and E)
G) A) and B)

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Malignant tumors need nutrients and oxygen to grow. From what structures do they obtain nutrients and oxygen?


A) Capillaries
B) Lymphatic vessels
C) Lungs
D) Kidneys
E) Arteries

F) C) and D)
G) A) and E)

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If a gene mutation occurs that results in a premature stop codon in the mRNA sequence, the protein will __________.


A) misfold
B) be incomplete
C) be normal
D) cause other proteins to misfold
E) be larger in size

F) All of the above
G) B) and E)

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During the division of eukaryotic cells, the ______ assists by dividing the genetic material and cell contents into the two resulting cells.


A) nucleus
B) centrioles
C) ribosomes
D) lysosome
E) mitochondria

F) B) and E)
G) C) and D)

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In which stage does the cell spend most of its time?


A) Interphase
B) Cytokinesis
C) Anaphase
D) Prophase
E) Telophase

F) A) and E)
G) A) and B)

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